![]() ![]() According to various reports in Ethiopia, the prevalence of bacterial CAP ranges from 38.7% to 45%. Sub-Saharan Africa also shows high levels of morbidity and mortality, with approximately 4 million cases of pneumonia occurring annually, resulting in about 200,000 deaths. In Africa, the mortality rate of CAP in adult patients varies between 6% and 15%. adults, and it is estimated to kill nearly one million adults per year in Asia. The annual incidence of CAP in Europe has been reported to be 1.6–10. Globally, CAP is a major cause of morbidity and mortality. ![]() The Infectious Diseases Society of America (IDSA) defines community-acquired pneumonia (CAP) as an acute infection of the pulmonary tissue accompanied by the presence of an acute infiltrate on chest radiograph or auscultatory findings consistent with pneumonia in a patient who did not acquire it from a health care system or within the first 48 hours after hospitalization. The two major categories of pneumonia are community and hospital-acquired. It is the most common disease with a high prevalence in the community and causes significant morbidity and mortality. Pneumonia is an inflammation of the lung parenchyma caused by an infectious agent. Statistical package for social sciences WHO, ![]() Methicillin-resistant Staphylococcus aureus SOPs, Infectious diseases society of America LRTIs, This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.ĭata Availability: All relevant data are within the manuscript and its Supporting Information files.įunding: The author(s) received no specific funding for this work.Ĭompeting interests: The authors have declared that no competing interests exist.Īntimicrobial susceptibility testing ATCC,Ĭlinically diagnosed community-acquired pneumonia CLSI,Ĭlinical and laboratory standards institute COPD,Ĭhronic obstructive pulmonary disease IDSA, Received: NovemAccepted: JanuPublished: February 1, 2022Ĭopyright: © 2022 Assefa et al. PLoS ONE 17(2):Įditor: Abdelazeem Mohamed Algammal, Suez Canal University, EGYPT Aging (AOR: 3.248, 95% CI: 1.001–10.545, p = 0.050), a history of pneumonia (AOR: 7.004, 95% CI: 3.591–13.658, p = 0.001), alcohol use (AOR: 6.614, 95% CI: 3.399–12.872, p < 0.001), and overcrowded living conditions (AOR: 4.348, 95% CI: 1.964–9.624, p = 0.001) were significantly associated with culture-positive sputum.Ĭitation: Assefa M, Tigabu A, Belachew T, Tessema B (2022) Bacterial profile, antimicrobial susceptibility patterns, and associated factors of community-acquired pneumonia among adult patients in Gondar, Northwest Ethiopia: A cross-sectional study. aureus isolates showed inducible clindamycin resistance. Overall, 72.2% of the isolates were multi-drug resistant to K. Gram-negative bacteria were susceptible to gentamicin (87.5%), azithromycin (87.1%), ciprofloxacin (86.6%), and ceftriaxone (79.0%) but highly resistant to ampicillin (100%), followed by tetracycline (87.1%), doxycycline (86.4%), co-trimoxazole (80.6%), and amoxicillin-clavulanic acid (79.0%). The gram-positive bacteria were susceptible to chloramphenicol (100%) and clindamycin (96.6%). ![]()
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